Publication
Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes
Single-cell and functional immunogenomic analysis identifying progressive tumor-resident NK cell dysfunction as a predictor of poor outcomes in advanced clear-cell renal cell carcinoma.
Citation
Xu W, Birch G, Melki A, Moritz V, Bharadwaj M, Schindler NR, Labaki C, Saliby RM, Dinh K, Horst JT, Sun M, Kashima S, Hugaboom M, Dighe A, Machaalani M, Lee GS-M, Hurwitz M, McGregor BA, Hirsch MS, Shukla SA, McDermott DF, Signoretti S, Romee R, Choueiri TK, Braun DA. Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes. ESMO Open. 2025;10(2):104105. doi:10.1016/j.esmoop.2024.104105.